Behavioral and Physiological Characterization of Sensorimotor Gating in the Goldfish Startle Response
نویسندگان
چکیده
منابع مشابه
Behavioral and physiological characterization of sensorimotor gating in the goldfish startle response.
Prepulse inhibition (PPI) is typically associated with an attenuation of auditory startle behavior in mammals and is presumably mediated within the brainstem startle circuit. However, the inhibitory mechanisms underlying PPI are not yet clear. We addressed this question with complementary behavioral and in vivo electrophysiological experiments in the startle escape circuit of goldfish, the Maut...
متن کاملTITLE Behavioral and physiological characterization of sensorimotor gating in the goldfish startle response AUTHORS
Prepulse inhibition (PPI) is typically associated with an attenuation of auditory startle behavior in mammals and is presumably mediated within the brainstem startle circuit. However, the inhibitory mechanisms underlying PPI are not yet clear. We addressed this question in behavioral and complementary in vivo electrophysiological experiments in the startle escape circuit of goldfish, the Mauthn...
متن کاملSensorimotor Gating: Startle Submits to Presynaptic Inhibition
Prepulse inhibition is a type of sensorimotor gating that is disrupted in some neuropsychiatric disorders. Its cellular basis has eluded investigators but now, using a molluscan model system, a cellular mechanism has been established.
متن کاملImpaired sensorimotor gating of the acoustic startle response in the prodrome of schizophrenia.
BACKGROUND Schizophrenia patients exhibit impairment in prepulse inhibition (PPI) of the acoustic startle response (ASR), which is commonly interpreted as a sensorimotor gating deficit. To date, it is unclear when these gating deficits arise. Results of animal studies and some human data suggest that PPI deficits are in part genetically determined, such that gating deficits could be present bef...
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ژورنال
عنوان ژورنال: Journal of Neurophysiology
سال: 2008
ISSN: 0022-3077,1522-1598
DOI: 10.1152/jn.00959.2007